Cellular Fate of a Modular DNA Delivery System Mediated by Silica Nanoparticles

Cellular fate of a modular DNA delivery system mediated by silica nanoparticles.

Development of efficient molecular medicines, including gene therapeutics, RNA therapeutics, and DNA vaccines, depends on efficient means of transfer of DNA or RNA into the cell. Potential problems, including toxicity and immunogenicity, surrounding viral methods of DNA delivery have necessitated the use of nonviral, synthetic carriers. To better design synthetic carriers, or transfection reage...

Functionalized Mesoporous Silica Nanoparticles as a Novel Antioxidant Delivery System

Antioxidants have an important role in control and prevention of dangerous diseases like cancers, but instability and high solubility of the antioxidants are <span style="font-size: 11pt; color: #00000...

Receptor-mediated cellular uptake of nanoparticles: a switchable delivery system.

8 The small size of nanoparticles and nanocages enables them to overcome various biological barriers and enter target cells, which is an attractive feature for various applications in biomedicine. For example, quantum dots, gold, and magnetic nanoparticles have been used as delivery carriers for small-interference RNA (siRNA), which has been applied for silencing specifi c genes in vitro and in...

control of the optical properties of nanoparticles by laser fields

در این پایان نامه، درهمتنیدگی بین یک سیستم نقطه کوانتومی دوگانه(مولکول نقطه کوانتومی) و میدان مورد مطالعه قرار گرفته است. از آنتروپی ون نیومن به عنوان ابزاری برای بررسی درهمتنیدگی بین اتم و میدان استفاده شده و تاثیر پارامترهای مختلف، نظیر تونل زنی(که توسط تغییر ولتاژ ایجاد می شود)، شدت میدان و نسبت دو گسیل خودبخودی بر رفتار درجه درهمتنیدگی سیستم بررسی شده اشت.با تغییر هر یک از این پارامترها، در...

Live-cell imaging of drug delivery by mesoporous silica nanoparticles